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Fostering innovation and collaboration in liver research
About the Liver Center
The UCSF Liver Center is one of 17 Digestive Diseases Research Core Centers (DDRCC) in the United States, whose purpose is to enhance research productivity and collaboration among scientists with similar interests.
Research Themes of the Center
The overall focus of the Center is on integrative biology of the liver. Research in the Center is organized into 3 themes: Liver Injury, Repair & Transplantation​, Hepatic Metabolism & Metabolic Derangements, Liver Cell Biology, Plasticity & Transformation​.
Core Services of the Center
The Liver Center operates four biomedical core facilities to expedite and enhance the research performed by Center members. The Cores are designed to provide liver-specific services that are unavailable elsewhere within or outside UCSF.

Welcome to the UCSF Liver Center

The Liver Center is a consortium of 60 researchers who share a common interest in liver biology and disease. The goal of the Center is to integrate bench science with clinical investigation, in support of its vision to understand and cure human liver diseases.

The physicians and scientists of the Liver Center are committed to improving understanding of liver biology and alleviating suffering from liver diseases. Read More.

Jacquelyn Maher, MD

Program Director, Liver Center


Featured Publications

Sun JC, Lanier LL. Is There Natural Killer Cell Memory and Can It Be Harnessed by Vaccination? NK Cell Memory and Immunization Strategies against Infectious Diseases and Cancer. Cold Spring Harb Perspect Biol. 2017 Dec 18 [Epub ahead of print] PMID: 29254979.

Lai JC, Covinsky KE, McCulloch CE, Feng S. The Liver Frailty Index Improves Mortality Prediction of the Subjective Clinician Assessment in Patients With Cirrhosis. Am J Gastroenterol. 2017 Dec 12 [Epub ahead of print] PMID: 29231189.

Corbit KC, Camporez JPG, Edmunds LR, Tran JL, Vera NB, Erion DM, Deo RC, Perry RJ, Shulman GI, Jurczak MJ, Weiss EJ. Adipocyte JAK2 Regulates Hepatic Insulin Sensitivity Independently of Body Composition, Liver Lipid Content, and Hepatic Insulin Signaling. Diabetes. 2017 Dec 4 [Epub ahead of print] PMID: 29203511.

Upcoming National & International Conferences

Hepatic Fibrosis Single Topic Conference

SEPTEMBER 14–15, 2018

More Information & Registration


Liver Center News

2018 Pilot/Feasibility Grant Awardees

Jennifer Chen, MD

Dissecting the role of YAP and TAZ in hepatic stellate activation and liver fibrosis

Caroline Duwaerts, PhD

The role of regulated IRE1 dependent decay (RIDD) in endoplasmic reticulum stress-induced liver cell death


Aras Mattis, MD, PhD

Discovery of novel genes regulating intrahepatic steatosis in mice and humans


Suzanne Sharpton, MD

An integrated analysis of the human gut metabolome and metagenome in nonalcoholic fatty liver disease